0pt0 - I'm struggling to understand the letters you're left with because there doesn't appear to be a single simple slip or typo that would explain the confusion.
The misprint that completes the 7 letter word ('...G') is immediately followed by a key letter from your list, but you appear to have two additional letters before we get to it.
Similarly, I can't see a likely explanation for the 'U' you mention because there isn't a 'u' anywhere in that clue, let alone in its definition (although I agree with the letter you'd replace it with, because that is the last letter of the misprinted definition).
As you already know what the 2 key letters stand for - (and if you have the correct start to the message - the 3, 5, 7, parts) it should be fairly obvious what the missing two letter word would have to be to make a coherent sentence but as confirmation, here's the word/letter count leading up to the obvious thematic bit -
3, 5, 7, 2, 9, 2, ...