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You've got to know famous American animals also this one had a film made about him

Duplicate Post by Clivo

I have filled in all the crossword barring 16a The answer is obvious. But didn't clueless about this until someone mentioned truncatated tom.
That would have been a better clue.
It does not say the word "to" is shortened. Initially I took to? as a location. I suppose that would fit the first word

Impenetrable for me, apart from 22d.

Are there any anagrams?

Yep, try 12a and 11d…