Thanks to Kilgore Trout at 35 I now know what the strands are but, as previous contributors have said, the end game is a little hazy to me. I have an 8 letter strand, in a straight line for the 3 letter alterations, but cannot see anything in a straight line, up, down or diagonal, for the other strand. However, there is a 4 letter, near semi-circular, possibility on the RHS of the grid, but that would be too simple, wouldn't it? Maybe, when my head clears from an evening out last night, I'll look again.