HNY all! The forum has certainly been a bit quiet over the holiday period. Enjoyed this one, had a strong suspicion we were in for the alliterative threesome as soon as I saw the grid. My sticking point was 18d as I bunged in the wrong element to start with. The anagram in 23a is rather fun.
Yevrah, the drug is the last letter in 12a. I’m not sure if this chemical is the same thing though.