????????????? - 13 letter crossword answer

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Signalization

Significances

noun - a meaning that is not expressly stated but can be inferred; "the significance of his remark became clear only later"; "the expectation was spread both by word and by implication"
the message that is intended or expressed or signified; "what is the meaning of this sentence"; "the significance of a red traffic light"; "the signification of Chinese characters"; "the import of his announcement was ambiguous"
the quality of being significant; "do not underestimate the significance of nuclear power"

Significantly

adverb - in a significant manner; "our budget will be significantly affected by these new cuts"
in a statistically significant way; "the two groups differed significantly"
in an important way or to an important degree; "more importantly, Weber held that the manifold meaning attached to the event by the social scientist could alter his definition of the concrete event itself"

Signification

noun - the message that is intended or expressed or signified; "what is the meaning of this sentence"; "the significance of a red traffic light"; "the signification of Chinese characters"; "the import of his announcement was ambiguous"

Significative