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21 Shrewd replacing the h (hard) with c (about)

24 is SIOUAN. Native American. Every other pair of loSIng OUt wANTs.

As said before 23 is DIVEST. Strip is the definition. And art indicates an old formation, as in thou art diving, i.e. thou divest. I know you will hate that, but it is what it is

Thanks, yes, not liking that at all. Also not happy with keen = shrewd.

Wordwizard gives nothing for the letters I have for 37d - ?i?c?c?o?y - can't see any errors in that, am I missing something obvious?

I think this is discectomy

Column of the spinal variety

Duplicate Thread by Araucaria

31 down?e?t?e?i?e?a

victim of achilles heel is wretched one in confined area

PENTHESILEIA, victim of Achilles
[Anagram of HEEL IS] + I, all in PENT A(rea)

Penthesileia? Horrible clue, horrible answer.

queen of the amazons