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hugh - unhorse is correct (i had dehorse, then realised my error in the endgame).

restoril is a new one on me!

I was wrong. I had come with Excedril.
But now unhorse is confirmed I have finally got the real (childbirth) answer. So I can stop inventing new drugs now!

I have full grid now apart from a few letters missing in the silver words. I'm seriously confused as I have two Ps and an N for first and last letters, and malone is suggesting one starts and ends with R and I, - none of which appears in EG ALL ELK!! Throw me a line!

Lumen, the first and last letters given are those after the changes are made. Malone said that one starts with an E and ends with an L (given as a lower case, l)

I thought that. Surely the instruction should be the other way round?!
I can't see the bottom left one, but I have the other three. But I'm not really bothered...don't understand why it has been constructed this way. As all are real words, why not just clue the actual final words which cross the thematics?
At least the Listener was excellent this week.

Lumen, the bottom left is not specific. The first letter is probably the one you haven't yet used from EG ALL ELK.

I tend to self-prescribe 5a most frequently…..

I was held up for ages by falling into a trap of which I have been aware for over fifty years. I still fall for flower/flower!