Cymru and Jono 22d is used metaphorically (at least where I come from!) to mean addled or confused as in "I'm all ---- with this crossword..."
Took me a ridiculously long time to get LOI 8d, being a Welshman (still starting from snatching defeat from the jaws of victory at Twickenham yesterday) & therefore the wrong sort of Celt!
Otherwise pretty straightforward & fun Sunday brainteaser, thanks to Everyman.