The meta interpretation is to consider what the whole thing is, the name of the puzzle itself. It's very difficult to explain further without spoilering but the answer is very much staring us all in the face!
snowwhite: I’m afraid I don’t understand your way of getting to the theme - do you mean that you used the solutions to 5 and 9? I can just about see how the might work, but I’m pretty sure it’s not what Paul had in mind.
Philo: ‘take’ in the criminal sense - does that help?
Both 20 and, especially, 22 are pretty obscure theme words, at least for me. 20 parses as 3 letters inserted in a word for ‘cuddle’; 22 parses as (3,3), the cocktail coming first.