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Whetstone, I think it's just that a No One is a nobody, a failure.

Thanks Malone... NO ONE....understood....I don't like these loose definitions!

Thanks, Whetstone. I don't think it was a particularly good clue, just so-so!

Whetstone, I agree with Malone.
A "no one" is a nobody/failure.
And it is not a great clue!

2d. Make light of everything, having strayed out of bounds
ALLEVIATE

Parse?

All, everything
Eviate - Deviated, strayed. Out of bounds- drop the first and last letters.

Cheers malone, understood

7d. Greek department famous for ego therein
ARCADIA

Parse?

It's one of those classical allusions, references - to a famous quote, 'Et in Arcadia ego'.
Arcadia, Greek department.

Famous (one might say infamous) Poussin painting
https://en.wikipedia.org/wiki/Et_in_Arcadia_ego
There is a presistent story that decoding the inscription holds the key to finding the hidden treasure of the Cathars (except they probably didn't have any!)