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I quite enjoyed this one, and although 6d was one of the last to complete, I didn't have any real problem with it.
21d, though, I (still) can't see how the answer fits the clue. I was only reassured that my answer was correct from cerasus's post.

Smot First 4 letters for 'affected' followed by empty/vacuous t(****)s

oops t(*****)s

Thanks jazzgirl :-)

What's "its" doing in 23 ac? Doesn't help with parsing and seems superfluous ad well as misleading.