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Help appreciated with 7d. "Becoming callous and cool over time" I-D-R-T-O-.

Thank you Mamya. - Previous clues were no help to one as dumb as me, Chrise. Have now got it.
wordless

Cool , as in fashionable over time as in length of time - leading to obscure word meaning becoming callous.

Thanks Chrisxx. I'd forgotten about the medical callous.

ChrisE,
18d was my favourite clue too once the lower had dawned on me.
It shouldn't have taken me so long as I used it in that context in Joint Effort a while back.

Lovely clue, though, wasn't it, wordless (and rossim)?

I liked 18d and 24d, 27ac... Very satisfying. But I'm stuck in the NE corner. 8d, They comply, duffed up in cell. I have L???H?C?T? C may be wrong... 10ac, Charlie recollecting words of hippopotamus, ???D?? as well as 6d, Posh, like Victoria. P???M?. All help is welcome.

6 looks like plummy.

6d think fruit
10 think hippopotamus song

8 is an anagram of cell in the body.