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Dear Ixion: I hope you're getting some sleep nowadays, too. 4 am ? Be careful, young man, this, too, can become addctive!

Thankyou, Ixion. I should have looked up definitions of item!

This has been very helpful - I got the theme quite quickly, but am struggling with 36 down,

Essayist's trollop, once exquisite to the ear (4)

I have ?ICT but can't find a word that fits. Any help?

Silly me. The quote is there in Chambers. Apologies for being dim.

Belated thanks to bananabean for providing that much needed inspiration (only just able to get back here after yesterday), and to all for stopping me from giving up.

Hear, hear! It saved me, too!

..and the first letter of the first word? This is the non-thematic entry.

G