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22a To the French, all the same Republican cause? (6), and 12d First sample maybe that's hooked to second steroid (12). The answers look like Author and Testosterone, but I can't parse them fully?

22a To the French = AU, all the same, nevertheless = THO(UGH), Republican = R. Definition is cause, as in author of own misfortune.

12d First sample TESTER ONE, surrounding TO S (to second), ie TES(TOS)TERONE

Thanks, quisling