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12d State that is American at heart? (5,6).
Looks like 'Rhode Island' but I can't parse it.

18d Recalled piece about old commercial deficit (5,3)
Looks like 'price gap', but again, can't parse it.

RI is at the heart of ameRIcan

The other one looks like trade gap.
Part around aged in reverse.

Thank you Jono.

Can’t parse these:

3d Previous issue brought up I must introduce (3-4).
One-time?

46d Heavy, heavy blow above American boxing ring (7)
Onerous?

46 I think a Oner is a heavy blow, US is American and O is ring, circle.

3 Issue, emit, verb, brought up = reverse/upwards, so Time, One = I. Must introduce indicates that the One goes before Time, I think.)

Quite correct, Malone, this is what Chambers has to say about “oner”…

oner, one-er or wunner /wunˈər/ noun (all meanings informal or slang)
1. A person or thing unique or outstanding in any way
2. An expert
3. A single, uninterrupted action, process or operation (as in in a oner)
4. A £1 note
5. A heavy blow
6. A big lie

Thanks, Jono. My Chambers and I were in different parts of the house...

Thank you.