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Tough one this week . Help with these two might just get me there
51d) Turned up loudspeaker system for middle stage (4) I have ?u?a.
43d) Fellows study mostly a wreck (8) I have ?e?p?r?s

51 Pupa, middle stage (caterpillars) It's Up +PA/Public Address, loudspeaker system.

43 Hesperus, a famous wreck. He's Perus(al).

51d pupa. up and PA middle stage of development. Also stuck with 43d.
do you have 53a) fresh idea we run up the pole (9)?

Unwearied (anagram)

unwearied anag

Unwearied anagram

Many thanks Malone

You're welcome.