Just down to the bottom left of the puzzle and was wondering about these two:-
48 Ac - "Like certain cartoon with girl's name: watches that in French". (11) D-S-E---Q-E. It obviously ends in "que"
and the girl may well be "Di" but that's as far as I've got.
47 Down - "For example, hearing one's teacher" (6) ---S-I
Also, with regard to 54 Ac ("Screen villain doctor
turned to when speaking"), the answer would seem to be
"Hyde", but how does "when speaking" apply?