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I've found this week's crossword more tricky than usual. Having difficulty with three clues. 48d - a musical group and coming up, a larger one performing (5) n-n-t. The only word that seems to fit is ninut, as in magpie but unable to parse. 54a: US agent managed to turn round business (5) n-e-o. Finally, 5d: major university opens a computer device, unable to finish cryptic (9) a-b-e-o-s, I originally thought the answer was ambitious but sure 16a is tenderise. Any ideas? Thank you in advance :)

nonet

narco

ambiguous

tendering

5d
major : big
university :U
a mous(e)

54a managed : ran (reversed)
business : co
Narco (US narcotics officer)

nonet d musical geoup of nine

reversed: ten (larger than nine) on : performing

excuse typos

Thank you. It all makes sense now. I also entered 45d incorrectly as palremo instead of palermo, must try harder.