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22a
may be counted as a hazard in headquarters

p?l?e?

pollen

thankyou - that was the only word I could see that made any sense

You're welcome!

There has been some interesting discussion on this clue on fifteensquared - do you know the site?
http://www.fifteensquared.net/2014/09/22/guardian-26371-rufus/#comment-257328
Warning - it lists and parses all the answers, so don't look until you have finished or given up!