21d Strike North African on the way up to liquor shop (7)
Taproom (Liquor shop) - tap (strike) + room (moor backwards - a Moor being a North African)
25a In respect of intelligence at university first-rate (2,3)
Up top (brainy) - up (at university) + top (first-rate)
It helps if you post the entire clue, as then others who do not have the puzzle may be able to help
Dave