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18a Look after famous engineer.
22a They should succeed perhaps in English art work.

How many letters and have you got any already?

22 - Given earlier as "Heirs apparent" - anagram of "perhaps in E art"
18 afraid the only obvious thing is Brunel - engineer + Look - lo to give Brunello , a wine, but that makes no sense in the clue given?

this is the clue AB

Look after famous engineer with Italian red wine (8)

Brunel + lo

Thank you, Shooty.

No Worries AB. I think smudge may be new to the site. If so, Welcome. : )

thank you for the help