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22D Lapsed party's independent (4) ?L?D
looks like SLID but not seeing wordplay
5D Newcastle endlessly, excessively (5) T?O
looks like TOO...can't see work for Newcastle with a letter removed though?

5d TOON?

Sorry - it's five letters!

there is a reference to Newcastle Toon so too is correct rambler

22d There used to be Social and Liberal Democrats - do you think with the I that would give you SLID?

seems reasonable rambler...thanks

The Ann Walker clue is an anagram, and the town is New Lanark.

Hope this helps.

P

Stuck on last one
Screen messenger(4)
_r_s
Something to do with computers?

Iris was the messenger of the gods and is a screen n one's eye?

Thanks AB. Should have got that. Was on the wrong track