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As the cure for Mal de Mer, I don't eat at sea (8)

Corrective remedy used against initial digestion of toxic elements (8)

A frayed tied knot, although lacking 1000, can be used as a cure.

Sorry, typo on post 20. It should have read,

Remedy before one small spot infects (8)

Not sure it works all that well, maybe this is a bit better,

Poisoners undoing? (8)

Rather amazed to discover one "antidote" def is "remedy for sin". You really do learn all the time on here!

Some great entries this week; difficult to choose but in the end had to plump for;

Aristo no.27 with his revised;

"Rum in tea? Taking a spot is good for what ails you"

Your prize is a British reply to tech obsession;

http://www.youtube.com/watch?v=kAG39jKi0lI

Well done, aristo - great clue. Thanks for the prize, paul - the "One Ronnie" had passed me by - very funny. Was that Harry Enfield as the greengrocer?

congrats aristophanes

Well done aristo , I do like the way that you use rum...

Excellent clue Aristo, well done.