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I've not done at all well this week, and need help with:-
12a 'Pleasurable activity' (7) cant seem to get leisure to fit-in with exsisting letters!
5d 'Sliding note' (9)
38d ''Too valuable to be changed' (10)
42a 'Devastate, Damage extensivly'
Chances are that some of my existing answers are incorrect!

5d glissando?

languor
glissando
sacrosanct
ravage

Thanks very much for your help!
As in my school reports:-
"Must try harder"