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Hi folks having a brain freeze at the moment 1d (4-6) publisher initially concocts a great run for hard to put down publication. 2d (6) it's a weakness to abandon the cause. 3d (5) nothing left if so headed. 20a (4) from the mouth of some sailor aloft. Very grateful for any help. Thanks in advance.

1d looks like page turner, its an anagram

2d) defect

20a) oral (in the clue)

Thanks - just a few to go now

Sorry also need help on 10a (8) from one side to the other he wavers with a 2nd alternative. ( really can't think straight this week )

Defector

Thanks mamya

Thanks to everyone for your help, finally got it finished.