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5d Tasteful italian sauce covering duck penne's centre up (8) U?V?????

6d One nicker to limit volume, getting sound off (7) I?V????

12a Mostly secular American ruler killed by his son (5) ????S

Any ideas please?

Ah! Think 12a may be LAIUS from lai(c) us ?

and I think 6d could be INVEIGH

Typical - as soon as you post, you get them yourself!