Only two left but I'm stuck (at least the anthropology bit of my degree finally came in useful, deacades later...)
10A Utter fool's ebbing interest P...I.E
6D Scoffed in compiler's absence? N...E.
I assume it's N...ED, and I thought of nommed, as in LOLcatspeak! (no me + what?). Or is it a word with 'i' or 'me' taken out?
ISAAC: I thought it was ISA + AC for account.