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Hi everyone bottom left corner wont go in these will help.
20,across, Hospital doctor injecting substance right into bottom(9)
16,down,Name a whale briefly seen around stern of icebreaker(7)

have you got any letters towrds these yet, or is this corner a total void?

16 Narwhal

16d could be Narwhal

KK

Hi. 16D is Narwhal. 20A is registrar (injecting gist into rear). Hope this helps

Has anyone got 10a: After changes in statement leaves Irish town (----R-O-D), or 26a: Lie about closure of dance floor (-T-R-Y), yet? Thanks in advance.

Hi.

26a looks like storey ('story'/lie about last letter of 'dance').

JimC

Hi again.

10. Waterford ('word' about anagram of 'after').

JimC

Cheers Jim for Waterford; funnily enough I got Storey shortly after I asked!

Last one I need is 23a: Cast in low spirits, mostly, at the end of revue (H-A--)

I think it is heave.(throw,cast)

heavy(hearted)mostly = heav + last letter of revue.