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Please, please can someone help with my last 3 clues?

20 down - 9 letters - a lack of strictness

L ? O ? E ? E ? ?

39 across - Not ordered - 12 letters

U ? S ? ? ? E ? A ? I ?

5 down - medicine to destroy worms (12 letters)

A ? T ? E ? M ? N ? I ?

Many thanks in advance.

20d looseness

39a Unsystematic

Thanks so much dandelion - really grateful to you.

Anthelmintic

Thanks Trevor - don't think I would have got that in a month of Sundays!!! Really appreciate your help.