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24a Reluctant to throw out the first swear word 4
o?t?
9a Trained in biology perhaps so keeping nice and fit working out 10 s???n???i?
4dCream offering reduced energy with fewer calories 5 ????e
2d physical collapse I encountered during marathon perhaps 4 r???
Thanks for help

Hi Roger.

24a (L)OATH.
9a SCIENTIFIC (an anagram).
2d RUIN ('run' + 'i').

JimC

4d is ELITE (E for energy + LITE for reduced calories).

Thanks Jim C couldn't work last few out but can
see them now thanks for explaining.