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I would appreciate any help with the following clues.Thanks.
3 down- Accepting help I zapped extremes of exiguous lentigo(7)E?????S
6 down- A thousand laid off by struggling steelworks without defence?(9)Toothless?
10 down- Border taken up round eastern garb in faith school(9)?????S?E?
8 down- Shetland ducks featuring in early ART AUTRE(5)?????
22 down- line as in unthinking memory called up(7)E?U????

22 equator

3d lentigo is the def - anagram of help i inside es(extremes of exiguous)
6d anagram of steelworks less K(thousand)
10d 3 letter word for border - backwards with E synonym for garb inside
8d it's within the last3 words defn shetland ducks
22d imaginary line round the earth

6 Down looks more like 'towerless'. This'd fit in with 'without defence'and is an anagram of 'steelworks' less the 'k'(thousand laid off).

6 towerless ?
Not sure, but it is an anagram of steelwor(k)s

3d. ephelis

10d. medresseh

Many thanks samak,sudokulover Chips and DickI :)