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8d - Esau? If so, why?
16d - Alarm Bell? but what does clue mean?

What are the clues.pleaae?

Oops, sorry for breach of protocol!

8d - Head of State will want a Sunday Times. (4)

16d - Jolly bunch trapped in a laboratory - 'orrible situation sends a warning signal. (5,4)

8 down is ERAS. Head of state is ER (Elizabeth Regina) with A S (Sunday) gives ERAS = Times.

ALARM BELL is Royal Marines (RM) trapped in A LAB and 'orrible situation is 'ELL gives ALARM BELL

Head of state - ER + a + sunday (s) gives "eras" times.
A la rm b 'ell looks right, although I'm not with teh whole wordplay. with the " a lab" giving the laboratory and the 'ell being the 'orrible situation.

Nice work - thank you both. Is the connection with the RM's 'Jolly Sailor Man?

RM is Royal Marines = sailors = jolly bunch

The nick name of the Royal Marines are the JOLLIES.