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basically your genetic makeup. im sure that others could come up with better explanation.

Sorry to be a nuisance, but how does the clue work to give genome

courtesy of Terry

concerning = on
say = eg
revoutionary makes it...ge no + me (writer of clue).

Well thanks to you and Terry for that. Nice to know that I would never have got it in a million years. It's definitely over and out on the Mail crossword today for me. Maybe I should go back to the Telegraph.

i used to do the DT, and quite honestly i prefer it.