3 down Occur as a result (9)
E-E-T-A-E
7 down Witch (11)
E---A---E-S
21 across Cactus drug (6)
P-Y---
35 down One hostile to culture (10)
P-----T-N-
38 across Pursuit of pleasure (8)
-E-O---M
I think my brain went to sleep with this crossword so any help to finish it would be appreciated.