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Stuck on one seemingly impenetrable clue.

Act of Chancellor? Cashier due to slip on Twitter? (5)

?OOCE

The wordplay is DO ('Act') O ('of') CE ('Chancellor [of the Exchequer]'); DOOCE means to dismiss someone as a result of comments they have made on social media (the original reference being to Heather B Armstrong's blog at dooce,com).

Thanks - I refuse to use Social Media - unless this kind of site counts!